| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50427882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_940879 (CHEMBL2330498) |
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| Ki | 8400±n/a nM |
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| Citation |  Prezzavento, O; Arena, E; Parenti, C; Pasquinucci, L; Aricò, G; Scoto, GM; Grancara, S; Toninello, A; Ronsisvalle, S Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity. J Med Chem56:2447-55 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50427882 |
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| n/a |
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| Name | BDBM50427882 |
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| Synonyms: | CHEMBL2324617 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H30N2OS2 |
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| Mol. Mass. | 378.595 |
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| SMILES | O=C(CCCCC1CCSS1)N1CCN(CCc2ccccc2)CC1 |
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| Structure | 
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