Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50427883 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_940879 (CHEMBL2330498) |
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Ki | 1800±n/a nM |
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Citation | Prezzavento, O; Arena, E; Parenti, C; Pasquinucci, L; Aricò, G; Scoto, GM; Grancara, S; Toninello, A; Ronsisvalle, S Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity. J Med Chem56:2447-55 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50427883 |
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n/a |
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Name | BDBM50427883 |
Synonyms: | CHEMBL2324616 |
Type | Small organic molecule |
Emp. Form. | C19H28N2OS2 |
Mol. Mass. | 364.568 |
SMILES | O=C(CCCCC1CCSS1)N1CCN(Cc2ccccc2)CC1 |
Structure |
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