| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-1 |
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| Ligand | BDBM50428074 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_941622 (CHEMBL2330704) |
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| IC50 | 360000±n/a nM |
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| Citation |  Zhang, Y; Albohy, A; Zou, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. J Med Chem56:2948-58 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-1 |
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| Name: | Sialidase-1 |
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| Synonyms: | NANH | NEU1 | NEUR1_HUMAN | Sialidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45463.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960639 |
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| Residue: | 415 |
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| Sequence: | MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
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| BDBM50428074 |
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| n/a |
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| Name | BDBM50428074 |
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| Synonyms: | CHEMBL2325808 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N4O7 |
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| Mol. Mass. | 316.2673 |
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| SMILES | CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=[N+]=[N-] |r,c:6| |
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| Structure | 
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