| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50428072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_941624 (CHEMBL2330706) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Zhang, Y; Albohy, A; Zou, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. J Med Chem56:2948-58 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | nanH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88686.49 |
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| Organism: | Vibrio cholerae |
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| Description: | ChEMBL_941624 |
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| Residue: | 807 |
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| Sequence: | MSIKMTSQRRRASIHKETDSNIKGVDMRFKNVKKTALMLAMFGMATSSNAALFDYNATGD
TEFDSPAKQGWMQDNTNNGSGVLTNADGMPAWLVQGNGGRAQWTYSLSTNQHAQASSFGW
RMTTEMKVLSGGMITNYYANGTQRVLPIISLDSSGNLVVEFEGQTGRTILATGTAATEYH
KFELVFLPGSNPSASFYFDGKLIRDNIQPTASKQNMIVWGNGSSNTDGVAAYRDIKFEIQ
GDVIFRGPDRIPSIVASSVTPGVVTAFAEKRVGGGDPGALSNTNDIITRTSRDGGITWDT
ELNLTEQINVSDEFDFSDPRPIYDPSTNTVLVSYARWPTDAAQNGDRIKPWMPNGIFYSV
YDVASGNWRAPIDVTDQVKERSFQIAGWGGSELYRRNTNLNSQQDWQSNAKIRIVDGAAN
QIQVADGGRKYVFTLSIDESGSLVANLNGVSDPIILQSERAKVHSFHDYELQYSALNRST
TLFVDGQAITTWTGEVSQENNIQFGNADAQIDGRLHVQNIALTQQGQNLVEFDAFYLAQQ
TPEVEKDLEKLGWTKIKTGNTMSLYGNASVNPGPGHGITLTRQQNISGSQNGRLIYPAIV
LDRFFLNVMSIYSDDGGSNWQTGSTLPIPFRWKSSSILETLEPSEADMVELQNGDLLLTA
RLDFNQIVNGVNYSPRQQFLSKDGGITWSLLEANNANVFSNISTGTVDASITRFEQSDGS
HFLLFTNPQGNPAGTNGRQNLGLWFSFDEGVTWKGPIQLVNGASAYSDIYQLDSENAIVI
VETDNSNMRILRMPITLLKQKLTLSQN
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| BDBM50428072 |
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| n/a |
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| Name | BDBM50428072 |
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| Synonyms: | CHEMBL2325810 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N5O4 |
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| Mol. Mass. | 407.4225 |
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| SMILES | CC(=O)N[C@H]1[C@H](CNc2ccc(cc2)-c2ccccc2)OC(=C[C@@H]1N=[N+]=[N-])C(O)=O |r,c:23| |
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| Structure | 
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