| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-C chemokine receptor type 2 |
|---|
| Ligand | BDBM50428327 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_947374 (CHEMBL2344607) |
|---|
| Ki | 0.600000±n/a nM |
|---|
| Citation |  Abdel-Magid, AF Targeting CCR2 Receptor To Treat Inflammation Diseases and Disorders. ACS Med Chem Lett4:371-2 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-C chemokine receptor type 2 |
|---|
| Name: | C-C chemokine receptor type 2 |
|---|
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41932.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41597 |
|---|
| Residue: | 374 |
|---|
| Sequence: | MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
|
|
|
|---|
| BDBM50428327 |
|---|
| n/a |
|---|
| Name | BDBM50428327 |
|---|
| Synonyms: | CHEMBL2338392 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H30Cl2FN5O3 |
|---|
| Mol. Mass. | 526.431 |
|---|
| SMILES | CO[C@@H]1COCC[C@@H]1NC1CCN(CC1)C(=O)c1nc(CF)nc(Nc2ccc(Cl)c(Cl)c2)c1C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
