| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
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| Ligand | BDBM50428376 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_942101 (CHEMBL2340799) |
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| Ki | 330±n/a nM |
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| Citation |  Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. Bioorg Med Chem21:1564-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 14 |
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| Name: | Carbonic anhydrase 14 |
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| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37665.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme. |
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| Residue: | 337 |
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| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
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| BDBM50428376 |
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| n/a |
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| Name | BDBM50428376 |
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| Synonyms: | CHEMBL2333963 | Isopropyl 2,4-Dihydroxybenzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12O4 |
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| Mol. Mass. | 196.1999 |
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| SMILES | CC(C)OC(=O)c1ccc(O)cc1O |
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| Structure | 
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