| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50206215 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_942129 (CHEMBL2341285) |
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| Ki | 4320±n/a nM |
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| Citation |  Davis, RA; Vullo, D; Maresca, A; Supuran, CT; Poulsen, SA Natural product coumarins that inhibit human carbonic anhydrases. Bioorg Med Chem21:1539-43 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50206215 |
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| n/a |
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| Name | BDBM50206215 |
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| Synonyms: | 7,8-Dihydroxy-6-methoxy-chromen-2-one | 7,8-dihydroxy-6-methoxy-2H-chromen-2-one | CHEMBL54909 | FRAXETIN |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8O5 |
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| Mol. Mass. | 208.1675 |
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| SMILES | COc1cc2ccc(=O)oc2c(O)c1O |
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| Structure | 
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