| Reaction Details |
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 | Report a problem with these data |
| Target | LD26647p |
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| Ligand | BDBM10880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_942137 (CHEMBL2341293) |
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| Ki | 78±n/a nM |
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| Citation |  Syrjänen, L; Tolvanen, ME; Hilvo, M; Vullo, D; Carta, F; Supuran, CT; Parkkila, S Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two newa-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster. Bioorg Med Chem21:1516-21 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| LD26647p |
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| Name: | LD26647p |
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| Synonyms: | CAH2 | Carbonic anhydrase 2, isoform A | Dmel_CG6906 | LD26647p |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37674.24 |
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| Organism: | Drosophila melanogaster |
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| Description: | ChEMBL_942137 |
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| Residue: | 335 |
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| Sequence: | MRRCRNTPFAIVIAPILICASLVLAQDFGYEGRHGPEHWSEDYARCSGKHQSPINIDQVS
AVEKKFPKLEFFNFKVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFE
QFHFHWGENDTIGSEDLINNRAYPAELHVVLRNLEYPDFASALDKDHGIAVMAFFFQVGD
KSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTW
IDFTTPIDITEKQLNAFRLLTANDDHLKNNFRPIQPLNDRTLYKNYIEIPIHNMGSIPLV
DAENAAGKWRAQAAAVLLPLVVLAALSRTSIFRGF
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| BDBM10880 |
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| n/a |
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| Name | BDBM10880 |
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| Synonyms: | AZA | AZA2 | AZM acetazolamide | Acerazolamide, AAZ | Acetazolamide | Acetazolamide (AAZ) | Acetazolamide (AZA) | Acetazolamide (AZM) | Acetazolamide, 5 | Acetazolamide, AAZ | Acetazolamide, AZA | Acetazolamide, AZM | CHEMBL20 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Sulfonamide, 1 | US10172837, Acetazolamide | US11278534, Example acetazolamide | US11535599, Example acetazolamide | sulfonamide 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H6N4O3S2 |
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| Mol. Mass. | 222.245 |
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| SMILES | CC(=O)Nc1nnc(s1)S(N)(=O)=O |
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| Structure | 
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