Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCarbonic anhydrase 7
LigandBDBM50429908
Substrate/Competitorn/a
Meas. Tech.ChEMBL_945279
pH7±n/a
Kd 0.220000±n/a nM
Commentsextracted
Citation Dudutiene VZubriene ASmirnov AGylyte JTimm DManakova EGražulis SMatulis D 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. Bioorg Med Chem 21:2093-106 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50429908
n/a
NameBDBM50429908
Synonyms:CHEMBL2333411
TypeSmall organic molecule
Emp. Form.C13H6F4N2O2S3
Mol. Mass.394.388
SMILESNS(=O)(=O)c1c(F)c(F)c(Sc2nc3ccccc3s2)c(F)c1F
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: