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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Heparanase | ||
| Ligand | BDBM30704 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_950896 (CHEMBL2349720) | ||
| Kd | >1000000±n/a nM | ||
| Citation |  Gozalbes, R; Mosulén, S; Ortí, L; Rodríguez-Díaz, J; Carbajo, RJ; Melnyk, P; Pineda-Lucena, A Hit identification of novel heparanase inhibitors by structure- and ligand-based approaches. Bioorg Med Chem21:1944-51 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Heparanase | |||
| Name: | Heparanase | ||
| Synonyms: | Endo-glucoronidase | HEP | HPA | HPA1 | HPR1 | HPSE | HPSE1 | HPSE_HUMAN | HSE1 | Heparanase 50 kDa subunit | Heparanase 8 kDa subunit | Heparanase-1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 61167.67 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_327900 | ||
| Residue: | 543 | ||
| Sequence: |
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| BDBM30704 | |||
| n/a | |||
| Name | BDBM30704 | ||
| Synonyms: | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate | CHEMBL19215 | METERGOLINE | MLS000069437 | N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid (phenylmethyl) ester | N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid benzyl ester | SMR000059050 | benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate | cid_28693 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H29N3O2 | ||
| Mol. Mass. | 403.5167 | ||
| SMILES | CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13 | ||
| Structure | 
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