| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50432718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_952585 (CHEMBL2354098) |
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| Ki | 17±n/a nM |
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| Citation |  Thakur, GA; Bajaj, S; Paronis, C; Peng, Y; Bowman, AL; Barak, LS; Caron, MG; Parrish, D; Deschamps, JR; Makriyannis, A Novel adamantyl cannabinoids as CB1 receptor probes. J Med Chem56:3904-21 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50432718 |
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| n/a |
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| Name | BDBM50432718 |
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| Synonyms: | CHEMBL2348471 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H42O4 |
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| Mol. Mass. | 478.6628 |
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| SMILES | CC(C)(C)C(=O)OCC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:8,THB:30:29:26:32.31.33,30:31:28.29.34:26,33:31:28:34.25.26,33:25:28:32.30.31| |
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| Structure | 
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