| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
|---|
| Ligand | BDBM50432942 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_957667 (CHEMBL2378595) |
|---|
| IC50 | 33±n/a nM |
|---|
| Citation |  Gavara, L; Suchaud, V; Nauton, L; Théry, V; Anizon, F; Moreau, P Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors. Bioorg Med Chem Lett23:2298-301 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-3 |
|---|
| Name: | Serine/threonine-protein kinase pim-3 |
|---|
| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35888.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q86V86 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
|
|
|
|---|
| BDBM50432942 |
|---|
| n/a |
|---|
| Name | BDBM50432942 |
|---|
| Synonyms: | CHEMBL2377721 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H8N4 |
|---|
| Mol. Mass. | 172.1866 |
|---|
| SMILES | Nc1cc2cn[nH]c2c2cc[nH]c12 |
|---|
| Structure | 
|
|---|
Search and Browse
