| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM50432946 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_957667 (CHEMBL2378595) |
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| IC50 | 119±n/a nM |
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| Citation |  Gavara, L; Suchaud, V; Nauton, L; Théry, V; Anizon, F; Moreau, P Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors. Bioorg Med Chem Lett23:2298-301 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
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| BDBM50432946 |
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| n/a |
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| Name | BDBM50432946 |
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| Synonyms: | CHEMBL2377711 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4O2 |
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| Mol. Mass. | 306.3187 |
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| SMILES | CCc1[nH]c2c(cc3cn[nH]c3c2c1-c1ccccc1)[N+]([O-])=O |
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| Structure | 
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