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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transcriptional activator Myb | ||
| Ligand | BDBM43484 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_958516 (CHEMBL2383288) | ||
| IC50 | 2370±n/a nM | ||
| Citation |  Schomburg, C; Schuehly, W; Da Costa, FB; Klempnauer, KH; Schmidt, TJ Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships. Eur J Med Chem63:313-20 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transcriptional activator Myb | |||
| Name: | Transcriptional activator Myb | ||
| Synonyms: | MYB | MYB_CHICK | Proto-oncogene c-Myb | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 72474.34 | ||
| Organism: | Gallus gallus | ||
| Description: | ChEMBL_107588 | ||
| Residue: | 641 | ||
| Sequence: |
| ||
| BDBM43484 | |||
| n/a | |||
| Name | BDBM43484 | ||
| Synonyms: | (3aR,5R,5aR,8aR,9S,9aS)-5,8a-dimethyl-1-methylidene-9-oxidanyl-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-quinone | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | Helenalin | MLS000728512 | SMR000445626 | cid_23205 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H18O4 | ||
| Mol. Mass. | 262.301 | ||
| SMILES | C[C@@H]1C[C@H]2OC(=O)C(=C)[C@H]2[C@H](O)[C@@]2(C)[C@H]1C=CC2=O |c:17| | ||
| Structure | 
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