| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM50434076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_958427 (CHEMBL2382935) |
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| IC50 | 0.951000±n/a nM |
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| Citation |  Limpachayaporn, P; Wagner, S; Kopka, K; Hermann, S; Schäfers, M; Haufe, G Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography. J Med Chem56:4509-20 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
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| BDBM50434076 |
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| n/a |
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| Name | BDBM50434076 |
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| Synonyms: | CHEMBL2381343 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23FN2O6S |
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| Mol. Mass. | 414.448 |
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| SMILES | COC[C@@H]1CCCN1S(=O)(=O)c1ccc2N(CC[C@H](F)CO)C(=O)C(=O)c2c1 |r| |
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| Structure | 
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