| Reaction Details |
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 | Report a problem with these data |
| Target | Prostate-specific antigen |
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| Ligand | BDBM50099216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_959179 (CHEMBL2383462) |
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| IC50 | 226±n/a nM |
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| Citation |  Kostova, MB; Rosen, DM; Chen, Y; Mease, RC; Denmeade, SR Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors. J Med Chem56:4224-35 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostate-specific antigen |
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| Name: | Prostate-specific antigen |
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| Synonyms: | APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28747.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_959198 |
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| Residue: | 261 |
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| Sequence: | MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
SLYTKVVHYRKWIKDTIVANP
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| BDBM50099216 |
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| n/a |
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| Name | BDBM50099216 |
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| Synonyms: | (2S,3S)-1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-3-(4-hydroxy-benzyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester | 1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-3-(4-hydroxy-benzyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester | CHEMBL286934 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H29NO7 |
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| Mol. Mass. | 563.5966 |
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| SMILES | Oc1ccc(C[C@H]2[C@H](N(C(=O)Cc3cccc(c3)C(=O)OCc3ccccc3)C2=O)C(=O)OCc2ccccc2)cc1 |
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| Structure | 
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