| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-2 |
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| Ligand | BDBM50331683 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_960638 (CHEMBL2390091) |
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| IC50 | 9000±n/a nM |
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| Citation |  Albohy, A; Zhang, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4. ACS Med Chem Lett4:532-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-2 |
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| Name: | Sialidase-2 |
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| Synonyms: | Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960638 |
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| Residue: | 380 |
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| Sequence: | MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYD
APTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRAN
VTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYA
YRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHL
RARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH
SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYE
EIVFLMFTLKQAFPAEYLPQ
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| BDBM50331683 |
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| n/a |
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| Name | BDBM50331683 |
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| Synonyms: | (2R,3R,4S)-4-hydroxy-3-(2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetamido)-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylate | CHEMBL1289979 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O8 |
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| Mol. Mass. | 434.4 |
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| SMILES | OC[C@@H](O)[C@@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(=O)Cn1cc(nn1)-c1ccccc1)C(O)=O |r,c:8| |
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| Structure | 
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