| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PAK 2 |
|---|
| Ligand | BDBM50434333 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_960988 (CHEMBL2388904) |
|---|
| IC50 | 244±n/a nM |
|---|
| Citation |  Abdel-Magid, AF PAK1: A Therapeutic Target for Cancer Treatment. ACS Med Chem Lett4:431-2 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase PAK 2 |
|---|
| Name: | Serine/threonine-protein kinase PAK 2 |
|---|
| Synonyms: | PAK2 | PAK2_HUMAN | Serine/threonine-protein kinase PAK 1/PAK 2/PAK 3 | Serine/threonine-protein kinase PAK 2 | Serine/threonine-protein kinase PAK 2 (PAK2) | p21-Activated kinase 2 (PAK2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 58037.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13177 |
|---|
| Residue: | 524 |
|---|
| Sequence: | MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP
PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
|
|
|
|---|
| BDBM50434333 |
|---|
| n/a |
|---|
| Name | BDBM50434333 |
|---|
| Synonyms: | CHEMBL2386718 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18F2N8 |
|---|
| Mol. Mass. | 396.3966 |
|---|
| SMILES | C[C@H](Nc1nccc(Nc2cc(n[nH]2)C2CC2(F)F)n1)c1ccc2nc[nH]c2c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
