| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM50014210 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_964952 (CHEMBL2395820) |
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| Ki | >10000±n/a nM |
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| Citation |  Arunotayanun, W; Dalley, JW; Huang, XP; Setola, V; Treble, R; Iversen, L; Roth, BL; Gibbons, S An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'. Bioorg Med Chem Lett23:3411-5 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | H1R | HH1R | HISTAMINE H1 | HRH1 | HRH1_HUMAN |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 55808.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Cell pellets from SK-N-MC cells transfected with human H1 receptor were used in binding assay. |
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| Residue: | 487 |
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| Sequence: | MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKC
ETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLR
PENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKL
YCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR
TDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFI
MAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFK
RILHIRS
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| BDBM50014210 |
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| n/a |
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| Name | BDBM50014210 |
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| Synonyms: | 1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl)propan-2-amine | 3-(2-Aminopropyl)indole | CHEMBL30713 | DL-3-(2-Aminopropyl)indole | Indopan | alpha-Methyl-1H-indole-3-ethanamine | alpha-Methyl-3-indoleethanamine | alpha-Methyl-beta-indoleethylamine | alpha-methyltryptamine |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14N2 |
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| Mol. Mass. | 174.2423 |
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| SMILES | CC(N)Cc1c[nH]c2ccccc12 |
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| Structure | 
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