| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50435867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_963768 (CHEMBL2395767) |
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| Ki | 13±n/a nM |
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| Citation |  Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Synthesis and receptor binding studies of novel 4,4-disubstituted arylalkyl/arylalkylsulfonyl piperazine and piperidine-based derivatives as a new class ofs1 ligands. Eur J Med Chem64:488-97 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50435867 |
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| n/a |
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| Name | BDBM50435867 |
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| Synonyms: | CHEMBL1479800 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21BrN2O2S |
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| Mol. Mass. | 409.341 |
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| SMILES | Brc1ccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)cc1 |
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| Structure | 
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