| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 35 |
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| Ligand | BDBM38549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_964313 (CHEMBL2395575) |
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| EC50 | 50±n/a nM |
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| Citation |  Funke, M; Thimm, D; Schiedel, AC; Müller, CE 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. J Med Chem56:5182-97 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 35 |
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| Name: | G-protein coupled receptor 35 |
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| Synonyms: | G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 34085.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_33695097 |
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| Residue: | 309 |
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| Sequence: | MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
QDSLCVTLA
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| BDBM38549 |
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| n/a |
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| Name | BDBM38549 |
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| Synonyms: | 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazino]ethoxy]ethanol | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethanol | 4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid | 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-2-naphthoic acid | CHEMBL170358 | CHEMBL177880 | HYDROXYZINE PAMOATE | MLS000028605 | Pamoic acid | SMR000058728 | US11744839, Compound of formula 8 | cid_25096 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H16O6 |
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| Mol. Mass. | 388.3695 |
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| SMILES | OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O |
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| Structure | 
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