| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
|---|
| Ligand | BDBM50436761 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_971638 (CHEMBL2404057) |
|---|
| IC50 | 8520±n/a nM |
|---|
| Citation |  Bambi-Nyanguile, SM; Hanson, J; Ooms, A; Alpan, L; Kolh, P; Dogné, JM; Pirotte, B Synthesis and pharmacological evaluation of 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as novel thromboxane A2 receptor antagonists. Eur J Med Chem65:32-40 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thromboxane A2 receptor |
|---|
| Name: | Thromboxane A2 receptor |
|---|
| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
|---|
| Type: | Enyzme |
|---|
| Mol. Mass.: | 37445.28 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21731 |
|---|
| Residue: | 343 |
|---|
| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
|
|
|
|---|
| BDBM50436761 |
|---|
| n/a |
|---|
| Name | BDBM50436761 |
|---|
| Synonyms: | CHEMBL2402412 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20BrN3O4S |
|---|
| Mol. Mass. | 466.349 |
|---|
| SMILES | CCCCCNC(=O)NS(=O)(=O)c1cc(ccc1Oc1ccc(Br)cc1)C#N |
|---|
| Structure | 
|
|---|
Search and Browse
