| Reaction Details |
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 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Ligand | BDBM50438270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_973309 (CHEMBL2412696) |
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| Ki | 105100±n/a nM |
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| Citation |  Soares, FA; Sesti-Costa, R; da Silva, JS; de Souza, MC; Ferreira, VF; Santos, Fda C; Monteiro, PA; Leitão, A; Montanari, CA Molecular design, synthesis and biological evaluation of 1,4-dihydro-4-oxoquinoline ribonucleosides as TcGAPDH inhibitors with trypanocidal activity. Bioorg Med Chem Lett23:4597-601 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Name: | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Synonyms: | G3PG_TRYCR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39070.68 |
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| Organism: | Trypanosoma cruzi |
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| Description: | ChEMBL_973242 |
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| Residue: | 359 |
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| Sequence: | MPIKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMNTDAEYFAYQMRYDTVHGKFK
YEVTTTKSSPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAA
EGHLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHVVSNASCTTNCLAPIVHVLVK
EGFGVQTGLMTTIHSYTATQKTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQ
GKLTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRASKTYMKGILGYTDEELVSAD
FINDNRSSIYDSKATLQNNLPKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKDRSARL
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| BDBM50438270 |
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| n/a |
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| Name | BDBM50438270 |
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| Synonyms: | CHEMBL2408386 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17NO8 |
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| Mol. Mass. | 351.3081 |
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| SMILES | COc1ccc2c(c1)n(cc(C(O)=O)c2=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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