| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50438371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_976686 (CHEMBL2417092) |
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| Ki | 2.9±n/a nM |
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| Citation |  Kozma, E; Jayasekara, PS; Squarcialupi, L; Paoletta, S; Moro, S; Federico, S; Spalluto, G; Jacobson, KA Fluorescent ligands for adenosine receptors. Bioorg Med Chem Lett23:26-36 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50438371 |
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| n/a |
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| Name | BDBM50438371 |
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| Synonyms: | CHEMBL2413100 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H45N9O11S |
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| Mol. Mass. | 968 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(Nc3ccc(CC(=O)Nc4ccc(CC(=O)NCCNC(=S)Nc5ccc(C6C7C=CC(=O)C=C7Oc7cc(O)ccc67)c(c5)C(O)=O)cc4)cc3)ncnc12 |r,c:44,48| |
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| Structure | 
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