| Reaction Details |
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 | Report a problem with these data |
| Target | Tumor necrosis factor receptor superfamily member 6 |
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| Ligand | BDBM50439385 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_979855 (CHEMBL2422398) |
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| EC50 | 1995±n/a nM |
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| Citation |  Jung, SH; Suh, JH; Kim, EH; Kim, JT; Yoo, SE; Kang, NS The discovery of inhibitors of Fas-mediated cell death pathway using the combined computational method. Bioorg Med Chem Lett23:5155-64 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tumor necrosis factor receptor superfamily member 6 |
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| Name: | Tumor necrosis factor receptor superfamily member 6 |
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| Synonyms: | Apo-1 antigen | Apoptosis-mediating surface antigen FAS | Apt1 | CD_antigen=CD95 | FASLG receptor | Fas | TNR6_RAT | Tnfrsf6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36836.00 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_107643 |
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| Residue: | 324 |
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| Sequence: | MLWIMAVLPLVLAGPELNVRMQGTDSIFEGLELKRSVRETDNNCSEGLYQVGPFCCQPCQ
PGERKVKDCTTSGGAPTCHPCTEGEEYTDRKHYSDKCRRCAFCDEGHGLEVETNCTRTQN
TKCRCKENFYCNASLCDHCYHCTSCGLEDILEPCTRTSNTKCKKQSSNYKLLWLLILPGL
AILFVFIYKRYRKRQPGDPESGIPSPESVPMNVSDVNLNKYIWRTAEKMKICDAKKFARQ
HKIPESKIDEIEHNSPQDAAEQKIQLLQCWYQSHGKTGACQALIQGLRKANRCDIAEEIQ
AMVWEDHENSISNSRNENEGQSLE
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| BDBM50439385 |
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| n/a |
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| Name | BDBM50439385 |
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| Synonyms: | CHEMBL2420406 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15BrClNO3S |
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| Mol. Mass. | 476.771 |
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| SMILES | OC(=O)c1cc(Cl)ccc1NC(=O)C(Sc1ccc(Br)cc1)c1ccccc1 |
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| Structure | 
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