| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 9 |
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| Ligand | BDBM50439561 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_979939 (CHEMBL2422672) |
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| IC50 | 10.0±n/a nM |
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| Citation |  Gao, C; Cahya, S; Nicolaou, CA; Wang, J; Watson, IA; Cummins, DJ; Iversen, PW; Vieth, M Selectivity data: assessment, predictions, concordance, and implications. J Med Chem56:6991-7002 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 9 |
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| Name: | Cyclin-dependent kinase 9 |
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| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 42789.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 372 |
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| Sequence: | MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF
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| BDBM50439561 |
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| n/a |
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| Name | BDBM50439561 |
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| Synonyms: | CHEMBL1965660 | US9670191, F26 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11Cl2N5O |
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| Mol. Mass. | 348.187 |
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| SMILES | NC(=O)c1cc([nH]c1-c1ccc(Cl)cc1Cl)-c1ccnc(N)n1 |
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| Structure | 
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