| Reaction Details |
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 | Report a problem with these data |
| Target | Virulence factor transcriptional regulator MvfR |
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| Ligand | BDBM50440124 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_980942 (CHEMBL2427495) |
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| Kd | 1300±n/a nM |
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| Citation |  Zender, M; Klein, T; Henn, C; Kirsch, B; Maurer, CK; Kail, D; Ritter, C; Dolezal, O; Steinbach, A; Hartmann, RW Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulence. J Med Chem56:6761-74 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Virulence factor transcriptional regulator MvfR |
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| Name: | Virulence factor transcriptional regulator MvfR |
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| Synonyms: | Transcriptional regulator MvfR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37217.11 |
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| Organism: | Pseudomonas aeruginosa PA14 |
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| Description: | ChEMBL_107649 |
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| Residue: | 332 |
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| Sequence: | MPIHNLNHVNMFLQVIASGSISSAARILRKSHTAVSSAVSNLEIDLCVELVRRDGYKVEP
TEQALRLIPYMRSLLNYQQLIGDIAFNLNKGPRNLRVLLDTAIPPSFCDTVSSVLLDDFN
MVSLIRTSPADSLATIKQDNAEIDIAITIDEELKISRFNQCVLGYTKAFVVAHPQHPLCN
ASLHSIASLANYRQISLGSRSGQHSNLLRPVSDKVLFVENFDDMLRLVEAGVGWGIAPHY
FVEERLRNGTLAVLSELYEPGGIDTKVYCYYNTALESERSFLRFLESARQRLRELGRQRF
DDAPAWQPSIVETAQRRSGPKALAYRQRAAPE
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| BDBM50440124 |
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| n/a |
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| Name | BDBM50440124 |
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| Synonyms: | CHEMBL2426232 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H6F3N3O |
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| Mol. Mass. | 229.1586 |
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| SMILES | Nc1nnc(o1)-c1cccc(c1)C(F)(F)F |
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| Structure | 
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