| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50441574 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_986694 (CHEMBL2438011) |
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| IC50 | >100000±n/a nM |
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| Citation |  Maingot, L; Elbakali, J; Dumont, J; Bosc, D; Cousaert, N; Urban, A; Deglane, G; Villoutreix, B; Nagase, H; Sperandio, O; Leroux, F; Deprez, B; Deprez-Poulain, R Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group. Eur J Med Chem69:244-61 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50441574 |
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| n/a |
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| Name | BDBM50441574 |
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| Synonyms: | CHEMBL2437163 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28ClN3O2S |
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| Mol. Mass. | 397.963 |
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| SMILES | Clc1ccc(OCC(=O)NNC(=S)NCCCCC2CCCCC2)cc1 |
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| Structure | 
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