| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50442752 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_989362 (CHEMBL2443397) |
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| Ki | 120±n/a nM |
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| Citation |  Banerjee, A; Maschauer, S; Hübner, H; Gmeiner, P; Prante, O Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers. Bioorg Med Chem Lett23:6079-82 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50109.86 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_989362 |
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| Residue: | 468 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVPASPPASLLTPASEGSVQLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRAARALVCT
VWAISALVSFLPILMHWWRDKGAEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMA
FVYLRVFREAQKQVKKIDSCERRFLGSPARPPSPAPSPGSPLPAAAAAAPVANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRVARGSCAAAGDGPRASGCLAVARPPPSPGAASDD
DDDEEDVGAAPPAPLLEPWAGYNGGAARDSDSSLDERTPGGRASESKV
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| BDBM50442752 |
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| n/a |
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| Name | BDBM50442752 |
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| Synonyms: | CHEMBL2443004 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26FN5O2 |
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| Mol. Mass. | 411.4725 |
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| SMILES | COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCF)cc2)CC1 |
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| Structure | 
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