| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1B1 |
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| Ligand | BDBM50442908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1265864 (CHEMBL3039490) |
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| Ki | 620±n/a nM |
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| Citation |  De Bruyn, T; van Westen, GJ; Ijzerman, AP; Stieger, B; de Witte, P; Augustijns, PF; Annaert, PP Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol83:1257-67 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1B1 |
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| Name: | Solute carrier organic anion transporter family member 1B1 |
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| Synonyms: | LST1 | OATP1B1 | OATP2 | OATPC | SLC21A6 | SLCO1B1 | SO1B1_HUMAN | Solute carrier organic anion transporter family member 1B1 | Solute carrier organic anion transporter family member 1B1 (OATP1B1) | Thromboxane B2 |
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| Type: | Protein |
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| Mol. Mass.: | 76468.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y6L6 |
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| Residue: | 691 |
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| Sequence: | MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE
ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY
YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML
RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV
DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE
TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF
KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS
FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT
YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI
QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI
KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE
NGSVMDEANLESLNKNKHFVPSAGADSETHC
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| BDBM50442908 |
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| n/a |
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| Name | BDBM50442908 |
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| Synonyms: | CHEMBL1314749 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H54O8 |
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| Mol. Mass. | 638.8306 |
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| SMILES | CC(C)CCCC1(C)Oc2c(CCC(C)C)c3OC45C6CC(CC4C(=O)c3c(O)c2C=C1)C(O)C5(CCC(C)C(O)=O)OC6(C)C |c:33,TLB:42:34:19.20:23.22,22:21:18:42.43,24:23:34.32:19.20,33:32:18:42.43,35:34:19.20:23.22,23:18:42.43:32.21.20,THB:17:18:42.43:32.21.20,33:32:19.20:23.22,43:19:34.32:23.22| |
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| Structure | 
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