| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM50442958 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1276450 (CHEMBL3088546) |
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| IC50 | 48±n/a nM |
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| Citation |  Patel, JZ; Parkkari, T; Laitinen, T; Kaczor, AA; Saario, SM; Savinainen, JR; Navia-Paldanius, D; Cipriano, M; Leppänen, J; Koshevoy, IO; Poso, A; Fowler, CJ; Laitinen, JT; Nevalainen, T Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors. J Med Chem56:8484-96 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 63071.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00519 |
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| Residue: | 579 |
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| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
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| BDBM50442958 |
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| n/a |
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| Name | BDBM50442958 |
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| Synonyms: | CHEMBL3087183 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N2O3 |
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| Mol. Mass. | 296.3205 |
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| SMILES | COc1nn(C(C)c2ccc(cc2)-c2ccccc2)c(=O)o1 |
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| Structure | 
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