| Reaction Details |
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 | Report a problem with these data |
| Target | KiSS-1 receptor |
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| Ligand | BDBM50442976 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1276485 (CHEMBL3088609) |
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| Ki | 0.130000±n/a nM |
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| Citation |  Asami, T; Nishizawa, N; Matsui, H; Nishibori, K; Ishibashi, Y; Horikoshi, Y; Nakayama, M; Matsumoto, S; Tarui, N; Yamaguchi, M; Matsumoto, H; Ohtaki, T; Kitada, C Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activity. J Med Chem56:8298-307 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| KiSS-1 receptor |
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| Name: | KiSS-1 receptor |
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| Synonyms: | Gpr54 | KISSR_RAT | Kiss1r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42915.37 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1448383 |
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| Residue: | 396 |
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| Sequence: | MAAEATLGPNVSWWAPSNASGCPGCGVNASDGPGSAPRPLDAWLVPLFFAALMLLGLVGN
SLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAPVLAL
HRLSPGPHTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAP
TDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYA
AYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCGPQRQRRPHASAHSDRAAPH
SVPHSRAAHPVRVRTPEPGNPVRRSPSVQDEHTAPL
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| BDBM50442976 |
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| n/a |
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| Name | BDBM50442976 |
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| Synonyms: | CHEMBL3086280 |
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| Type | Small organic molecule |
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| Emp. Form. | C54H79N15O12 |
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| Mol. Mass. | 1130.2984 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)NC)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r,w:62.63| |
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| Structure | 
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