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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM50417287 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1278482 (CHEMBL3094589) | ||
| Kd | 0.320000±n/a nM | ||
| Citation |  Del Cadia, M; De Rienzo, F; Weston, DA; Thompson, AJ; Menziani, MC; Lummis, SC Exploring a potential palonosetron allosteric binding site in the 5-HT(3) receptor. Bioorg Med Chem21:7523-8 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
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| BDBM50417287 | |||
| n/a | |||
| Name | BDBM50417287 | ||
| Synonyms: | Aloxi | Aurothioglucose | PALONOSETRON | PALONOSETRON HYDROCHLORIDE | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H24N2O | ||
| Mol. Mass. | 296.4067 | ||
| SMILES | O=C1N(C[C@H]2CCCc3cccc1c23)[C@@H]1CN2CCC1CC2 |wU:4.14,wD:14.16,(.24,-11.26,;.24,-12.8,;1.58,-13.56,;1.58,-15.1,;.24,-15.88,;.24,-17.42,;-1.09,-18.19,;-2.42,-17.42,;-2.42,-15.88,;-3.77,-15.1,;-3.77,-13.56,;-2.43,-12.78,;-1.09,-13.56,;-1.09,-15.1,;2.91,-12.8,;2.91,-11.26,;4.25,-10.49,;5.58,-11.26,;5.58,-12.8,;4.25,-13.56,;4.79,-12.41,;3.77,-11.79,)| | ||
| Structure | 
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