| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin G |
|---|
| Ligand | BDBM50444295 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1278124 (CHEMBL3095812) |
|---|
| IC50 | 19000±n/a nM |
|---|
| Citation |  Lucas, SD; Gonçalves, LM; Carvalho, LA; Correia, HF; Da Costa, EM; Guedes, RA; Moreira, R; Guedes, RC Optimization of O3-acyl kojic acid derivatives as potent and selective human neutrophil elastase inhibitors. J Med Chem56:9802-6 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin G |
|---|
| Name: | Cathepsin G |
|---|
| Synonyms: | CATG_HUMAN | CG | CTSG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28860.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469016 |
|---|
| Residue: | 255 |
|---|
| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
|
|
|
|---|
| BDBM50444295 |
|---|
| n/a |
|---|
| Name | BDBM50444295 |
|---|
| Synonyms: | CHEMBL3093806 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H22N2O6S |
|---|
| Mol. Mass. | 478.517 |
|---|
| SMILES | CC(C)(C)C(=O)Oc1cn(c(CSc2nc3cc(ccc3o2)C(O)=O)cc1=O)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
