| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50273465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1282321 (CHEMBL3100268) |
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| EC50 | 0.170000±n/a nM |
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| Citation |  Risgaard, R; Jensen, M; Jørgensen, M; Bang-Andersen, B; Christoffersen, CT; Jensen, KG; Kristensen, JL; Püschl, A Synthesis and SAR study of a novel series of dopamine receptor agonists. Bioorg Med Chem22:381-92 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50273465 |
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| n/a |
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| Name | BDBM50273465 |
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| Synonyms: | (+/-)-trans-1-Propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol | CHEMBL3098131 | CHEMBL455497 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23NO |
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| Mol. Mass. | 245.3599 |
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| SMILES | CCCN1CCC[C@@H]2Cc3c(O)cccc3C[C@@H]12 |r| |
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| Structure | 
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