| Reaction Details |
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 | Report a problem with these data |
| Target | Delta carbonic anhydrase |
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| Ligand | BDBM10887 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1282543 (CHEMBL3101210) |
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| Ki | 392±n/a nM |
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| Citation |  Vullo, D; Del Prete, S; Osman, SM; De Luca, V; Scozzafava, A; Alothman, Z; Supuran, CT; Capasso, C Sulfonamide inhibition studies of thed-carbonic anhydrase from the diatom Thalassiosira weissflogii. Bioorg Med Chem Lett24:275-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta carbonic anhydrase |
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| Name: | Delta carbonic anhydrase |
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| Synonyms: | ca1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32261.40 |
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| Organism: | Thalassiosira weissflogii |
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| Description: | ChEMBL_107983 |
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| Residue: | 281 |
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| Sequence: | MEVDVVPNTKNYWQSSMCPVNVHWHLGTEHYSVGEYDENGSGPNGNVGVPYRRTLAEGEV
QDGFRCHHYDPDDEAYTRPYEWKHCIGMEVGETYEVHWPHSGAGACGTTYQYQTPFYDGV
FCNLDMETLQTLAPQDIANAVGVQGQIFTIVNDDTYYYPDLIRGWIVDEEMGMGQDIAMY
TGSTTGESRSNEICSSYSPITWQVDRKCHKISASSFDKLCYDMKMQRDDMSDDLYAHGSR
ELVTPEYVANNQQTRRLTEKHEHNHSHGHSHVRGHQHHQWF
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| BDBM10887 |
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| n/a |
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| Name | BDBM10887 |
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| Synonyms: | Sulfamate 7 | Topiramate (TPM) | US11535599, Example topiramate | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate |
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| Type | Small organic molecule |
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| Emp. Form. | C12H21NO8S |
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| Mol. Mass. | 339.362 |
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| SMILES | CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 |r| |
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| Structure | 
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