| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM50446073 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1283892 (CHEMBL3106505) |
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| IC50 | 27400±n/a nM |
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| Citation |  Tian, M; Abdelrahman, A; Weinhausen, S; Hinz, S; Weyer, S; Dosa, S; El-Tayeb, A; Müller, CE Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem22:1077-88 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | ATP receptor | P2RX4 | P2RX4_HUMAN | P2X4 | Purinergic receptor | Purinergic, P2X4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43374.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X4 0 HUMAN::Q99571 |
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| Residue: | 388 |
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| Sequence: | MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
MKKRLYYREKKYKYVEDYEQGLASELDQ
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| BDBM50446073 |
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| n/a |
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| Name | BDBM50446073 |
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| Synonyms: | CHEMBL3103405 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O2 |
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| Mol. Mass. | 370.4437 |
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| SMILES | COc1ccc(CCNC(=O)N2c3ccccc3C=Cc3ccccc23)cc1 |c:19| |
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| Structure | 
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