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TargetP2X purinoceptor 4
LigandBDBM50446076
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1283887
IC50>100000±n/a nM
Citation Tian MAbdelrahman AWeinhausen SHinz SWeyer SDosa SEl-Tayeb AMüller CE Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem 22:1077-88 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 4
Name:P2X purinoceptor 4
Synonyms:ATP receptor | P2X4 | P2rx4 | P2x4 | Purinergic receptor
Type:PROTEIN
Mol. Mass.:43443.55
Organism:Mus musculus
Description:ChEMBL_1283887
Residue:388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIP
DKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKRYYYRDKKYKYVEDYEQGLSGEMNQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50446076
n/a
NameBDBM50446076
Synonyms:CHEMBL1483754
TypeSmall organic molecule
Emp. Form.C19H20N2O
Mol. Mass.292.3749
SMILESCCN(CC)C(=O)N1c2ccccc2C=Cc2ccccc12 |c:15|
Structure
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