| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein arginine N-methyltransferase 1 [11-371] |
|---|
| Ligand | BDBM50446399 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1287204 (CHEMBL3112261) |
|---|
| IC50 | 6100±n/a nM |
|---|
| Citation |  Fontán, N; García-Domínguez, P; Álvarez, R; de Lera, ÁR Novel symmetrical ureas as modulators of protein arginine methyl transferases. Bioorg Med Chem21:2056-67 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein arginine N-methyltransferase 1 [11-371] |
|---|
| Name: | Protein arginine N-methyltransferase 1 [11-371] |
|---|
| Synonyms: | ANM1_HUMAN | HMT2 | HRMT1L2 | IR1B4 | PRMT1 | Protein arginine N-methyltransferase 1 (PRMT1) | Protein arginine methyltransferase 1 (PRMT1) | Protein-arginine N-methyltransferase 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 41506.52 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99873[11-371] |
|---|
| Residue: | 361 |
|---|
| Sequence: | MENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDE
VRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIV
KANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGL
IFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNAC
LIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYT
HWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRM
R
|
|
|
|---|
| BDBM50446399 |
|---|
| n/a |
|---|
| Name | BDBM50446399 |
|---|
| Synonyms: | CHEMBL3109664 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H24N2O5 |
|---|
| Mol. Mass. | 288.3401 |
|---|
| SMILES | OC(=O)CCCCCNC(=O)NCCCCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
