| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase |
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| Ligand | BDBM50404746 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1286565 (CHEMBL3110798) |
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| IC50 | 120800±n/a nM |
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| Citation |  de Sousa, LR; Ramalho, SD; Burger, MC; Nebo, L; Fernandes, JB; da Silva, MF; Iemma, MR; Corrêa, CJ; de Souza, DH; Lima, MI; Vieira, PC Isolation of arginase inhibitors from the bioactivity-guided fractionation of Byrsonima coccolobifolia leaves and stems. J Nat Prod77:392-6 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase |
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| Name: | Arginase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36149.67 |
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| Organism: | Leishmania amazonensis |
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| Description: | ChEMBL_107995 |
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| Residue: | 329 |
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| Sequence: | MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVF
DGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGT
VAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVL
KPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMV
SYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHV
NDTISDGRAIARCMMGETLLYTPHTSSKL
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| BDBM50404746 |
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| n/a |
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| Name | BDBM50404746 |
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| Synonyms: | NSC-115919 | PENTAACETYLQUERCETIN |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20O12 |
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| Mol. Mass. | 512.4191 |
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| SMILES | CC(=O)Oc1cc(OC(C)=O)c2c(c1)oc(-c1ccc(OC(C)=O)c(OC(C)=O)c1)c(OC(C)=O)c2=O |
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| Structure | 
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