| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
|---|
| Ligand | BDBM50448029 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1288931 (CHEMBL3117628) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Lamotte, Y; Faucher, N; Sançon, J; Pineau, O; Sautet, S; Fouchet, MH; Beneton, V; Tousaint, JJ; Saintillan, Y; Ancellin, N; Nicodeme, E; Grillot, D; Martres, P Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPAR¿ agonists. Bioorg Med Chem Lett24:1098-103 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor delta |
|---|
| Name: | Peroxisome proliferator-activated receptor delta |
|---|
| Synonyms: | NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49719.14 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1288931 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
|
|
|
|---|
| BDBM50448029 |
|---|
| n/a |
|---|
| Name | BDBM50448029 |
|---|
| Synonyms: | CHEMBL3115247 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C35H34N8 |
|---|
| Mol. Mass. | 566.6981 |
|---|
| SMILES | CCCCn1c(nc2ccccc12)-c1ccc2nn(CCC)c(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
