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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A/3B | ||
| Ligand | BDBM50452935 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_3039 (CHEMBL620657) | ||
| IC50 | 1479±n/a nM | ||
| Citation |  Swain, CJ; Baker, R; Kneen, C; Moseley, J; Saunders, J; Seward, EM; Stevenson, G; Beer, M; Stanton, J; Watling, K Novel 5-HT3 antagonists. Indole oxadiazoles. J Med Chem34:140-51 (1991) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A/3B | |||
| Name: | 5-hydroxytryptamine receptor 3A/3B | ||
| Synonyms: | Serotonin 3 (5-HT3) receptor | Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor | ||
| Type: | n/a | ||
| Mol. Mass.: | n/a | ||
| Description: | ASSAY_ID of EBI is 2974 | ||
| Components: | This complex has 2 components. | ||
| Component 1 | |||
| Name: | 5-hydroxytryptamine receptor 3B | ||
| Synonyms: | 5HT3B_RAT | Htr3b | Serotonin (5-HT) receptor | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 50328.78 | ||
| Organism: | Rattus norvegicus | ||
| Description: | EBI_11885 | ||
| Residue: | 437 | ||
| Sequence: |
| ||
| Component 2 | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 55428.70 | ||
| Organism: | RAT | ||
| Description: | 5-HT3 HTR3A RAT::P35563 | ||
| Residue: | 483 | ||
| Sequence: |
| ||
| BDBM50452935 | |||
| n/a | |||
| Name | BDBM50452935 | ||
| Synonyms: | CHEMBL37093 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H19N3O | ||
| Mol. Mass. | 305.3737 | ||
| SMILES | C1CN2CCC1C(C2)c1nc(no1)-c1ccc2ccccc2c1 |(19.98,-10.96,;21.55,-11.39,;20.73,-12.78,;22.24,-12.01,;22.23,-10.38,;20.81,-9.58,;19.42,-10.4,;19.43,-12.02,;18,-9.6,;16.68,-10.38,;15.37,-9.61,;15.34,-8.1,;17.97,-8.08,;14.03,-10.38,;14.02,-11.88,;12.7,-12.64,;11.36,-11.86,;10.05,-12.61,;8.74,-11.83,;8.77,-10.29,;10.09,-9.54,;11.4,-10.33,;12.71,-9.58,)| | ||
| Structure | 
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