| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycogen phosphorylase, muscle form |
|---|
| Ligand | BDBM50422216 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_70989 (CHEMBL680567) |
|---|
| Ki | 44668±n/a nM |
|---|
| Citation |  Pastor, M; Cruciani, G; Watson, KA A strategy for the incorporation of water molecules present in a ligand binding site into a three-dimensional quantitative structure--activity relationship analysis. J Med Chem40:4089-102 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glycogen phosphorylase, muscle form |
|---|
| Name: | Glycogen phosphorylase, muscle form |
|---|
| Synonyms: | Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 97097.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1449751 |
|---|
| Residue: | 842 |
|---|
| Sequence: | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI
|
|
|
|---|
| BDBM50422216 |
|---|
| n/a |
|---|
| Name | BDBM50422216 |
|---|
| Synonyms: | CHEMBL336310 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H14ClNO6 |
|---|
| Mol. Mass. | 255.653 |
|---|
| SMILES | OC[C@H]1O[C@@H](NC(=O)CCl)[C@H](O)[C@@H](O)[C@@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
