| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50002039 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_304044 (CHEMBL840221) |
|---|
| Ki | 363±n/a nM |
|---|
| Citation |  Peng, Y; Keenan, SM; Zhang, Q; Kholodovych, V; Welsh, WJ 3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies. J Med Chem48:1620-9 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42744.99 |
|---|
| Organism: | Cavia porcellus (domestic guinea pig) |
|---|
| Description: | P41144 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
|
|
|
|---|
| BDBM50002039 |
|---|
| n/a |
|---|
| Name | BDBM50002039 |
|---|
| Synonyms: | CHEMBL427546 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H24N2O3 |
|---|
| Mol. Mass. | 412.4804 |
|---|
| SMILES | [H][C@@]12Oc3c4c(CC5N(C)CCC14[C@@]5(O)Cc1cc(cnc21)-c1ccccc1)ccc3O |THB:3:4:13:8.11.10,14:13:4.5.6:8.11.10,9:8:13:4.5.6| |
|---|
| Structure | 
|
|---|
Search and Browse
