| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50002961 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_448555 (CHEMBL897704) |
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| Ki | 126±n/a nM |
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| Citation |  Sisto, A; Altamura, M; Cardinali, F; D'Andrea, P; Rossi, C; Fattori, D alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists. Bioorg Med Chem Lett17:4841-4 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK2R_CAVPO | Neurokinin 2 receptor | Neurokinin NK2 | Substance-K receptor | TACR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45106.00 |
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| Organism: | GUINEA PIG |
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| Description: | Neurokinin NK2 TACR2 GUINEA PIG::Q64077 |
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| Residue: | 402 |
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| Sequence: | MGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILA
HQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATK
CVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLR
HLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMA
GDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS
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| BDBM50002961 |
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| n/a |
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| Name | BDBM50002961 |
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| Synonyms: | CHEMBL237048 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H41N5O3S |
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| Mol. Mass. | 623.807 |
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| SMILES | CN1CCN(CCCNC(=O)[C@@H](Cc2ccccc2)NC(=O)C2(Cc3ccccc3C2)NC(=O)c2cc3ccccc3s2)CC1 |
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| Structure | 
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