Reaction Details |
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Target | Indolethylamine N-methyltransferase |
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Ligand | BDBM50000181 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1333667 (CHEMBL3231053) |
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IC50 | 9300±n/a nM |
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Citation | Rokach, J; Hamel, P; Hunter, NR; Reader, G; Rooney, CS; Anderson, PS; Cragoe, EJ; Mandel, LR Cyclic amidine inhibitors of indolamine N-methyltransferase. J Med Chem22:237-47 (1979) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Indolethylamine N-methyltransferase |
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Name: | Indolethylamine N-methyltransferase |
Synonyms: | Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_RABIT | Indolamine N-methyltransferase | Thioether S-methyltransferase |
Type: | PROTEIN |
Mol. Mass.: | 28949.17 |
Organism: | Oryctolagus cuniculus |
Description: | ChEMBL_108264 |
Residue: | 263 |
Sequence: | MEGGFTGGDEYQKHFLPRDYLNTYYSFQSGPSPEAEMLKFNLECLHKTFGPGGLQGDTLI
DIGSGPTIYQVLAACESFKDITLSDFTDRNREELAKWLKKEPGAYDWTPALKFACELEGN
SGRWQEKAEKLRATVKRVLKCDANLSNPLTPVVLPPADCVLTLLAMECACCSLDAYRAAL
RNLASLLKPGGHLVTTVTLQLSSYMVGEREFSCVALEKEEVEQAVLDAGFDIEQLLYSPQ
SYSASTAPNRGVCFLVARKKPGS
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BDBM50000181 |
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n/a |
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Name | BDBM50000181 |
Synonyms: | CHEMBL3228335 |
Type | Small organic molecule |
Emp. Form. | C11H16N2O4 |
Mol. Mass. | 240.2557 |
SMILES | OC(=O)\C=C\C(O)=O.CC1CCC2=NCCN12 |t:11| |
Structure |
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