| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-1 |
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| Ligand | BDBM50008099 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1338367 (CHEMBL3240243) |
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| IC50 | 2000±n/a nM |
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| Citation |  McGeary, RP; Schenk, G; Guddat, LW The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. Eur J Med Chem76:132-44 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-1 |
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| Name: | Arginase-1 |
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| Synonyms: | ARGI1_RAT | Arg1 | Liver-type arginase | Type I arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34976.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_108287 |
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| Residue: | 323 |
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| Sequence: | MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN
DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV
IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF
TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT
LSCFGTKREGNHKPETDYLKPPK
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| BDBM50008099 |
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| n/a |
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| Name | BDBM50008099 |
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| Synonyms: | CHEMBL1234777 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H12N4O3 |
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| Mol. Mass. | 176.1738 |
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| SMILES | N[C@@H](CCNC(=N)NO)C(O)=O |r| |
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| Structure | 
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