| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor |
|---|
| Ligand | BDBM50009716 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1345989 (CHEMBL3258023) |
|---|
| IC50 | 1.7±n/a nM |
|---|
| Citation |  Jones, CD; Suarez, T; Massey, EH; Black, LJ; Tinsley, FC Synthesis and antiestrogenic activity of [3,4-dihydro-2-(4-methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]-phenyl]methanone, methanesulfonic acid salt. J Med Chem22:962-6 (1979) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor |
|---|
| Name: | Estrogen receptor |
|---|
| Synonyms: | ESR1_RAT | Esr | Esr1 | Estr | Nr3a1 | estrogen alpha |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 67045.89 |
|---|
| Organism: | RAT |
|---|
| Description: | estrogen alpha 0 RAT::P06211 |
|---|
| Residue: | 600 |
|---|
| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAY
EFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPP
HVSPFLHPHGHQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMI
MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK
SCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSP
LVIKHTKKNSPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQG
KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI
HRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVP
LYDLLLEMLDAHRLHAPASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI
|
|
|
|---|
| BDBM50009716 |
|---|
| n/a |
|---|
| Name | BDBM50009716 |
|---|
| Synonyms: | Compound 133314 | TRIOXIFENE MESYLATE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H35NO6S |
|---|
| Mol. Mass. | 549.678 |
|---|
| SMILES | CS(O)(=O)=O.COc1ccc(cc1)C1=C(C(=O)c2ccc(OCCN3CCCC3)cc2)c2ccccc2CC1 |c:13| |
|---|
| Structure | 
|
|---|
Search and Browse
