| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium-dependent noradrenaline transporter |
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| Ligand | BDBM35229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1340418 (CHEMBL3253106) |
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| IC50 | 1600±n/a nM |
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| Citation |  Carnmalm, B; Rämsby, S; Renyi, AL; Ross, SB; Ogren, SO Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants. J Med Chem21:78-82 (1978) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium-dependent noradrenaline transporter |
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| Name: | Sodium-dependent noradrenaline transporter |
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| Synonyms: | Norepinephrine transporter | SC6A2_MOUSE | Slc6a2 | Sodium-dependent noradrenaline transporter |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 69260.85 |
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| Organism: | MOUSE |
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| Description: | Norepinephrine transporter 0 MOUSE::O55192 |
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| Residue: | 617 |
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| Sequence: | MLLARMNPQVQPELGGADPLPEQPLRPCKTADLLVVKERNGVQCLLASQDSDAQPRETWG
KKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYN
REGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSW
NSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLC
LMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFY
RLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFA
IFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSS
MGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTS
ILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINF
KPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLSIRGSLWERVAYGITPENEHHL
VAQRDVRQFQLRHWLAI
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| BDBM35229 |
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| n/a |
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| Name | BDBM35229 |
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| Synonyms: | 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine | 5-(gamma-methylaminopropyl)iminodibenzyl | CHEMBL72 | DESIPRAMINE HYDROCHLORIDE | DMI | Desipramin | Desipramine | Desmethylimipramine | N-(3-methylaminopropyl)iminobibenzyl | US9944618, Compound ID No. 174 | demethylimipramine | monodemethylimipramine | norimipramine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2 |
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| Mol. Mass. | 266.3807 |
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| SMILES | CNCCCN1c2ccccc2CCc2ccccc12 |
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| Structure | 
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