| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
|---|
| Ligand | BDBM50011344 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1352251 (CHEMBL3268969) |
|---|
| Ki | 0.180000±n/a nM |
|---|
| Citation |  Zlotos, DP; Jockers, R; Cecon, E; Rivara, S; Witt-Enderby, PA MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential. J Med Chem57:3161-85 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1A |
|---|
| Name: | Melatonin receptor type 1A |
|---|
| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39392.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48039 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
|
|
|
|---|
| BDBM50011344 |
|---|
| n/a |
|---|
| Name | BDBM50011344 |
|---|
| Synonyms: | CHEMBL3260982 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22N2O4 |
|---|
| Mol. Mass. | 330.3783 |
|---|
| SMILES | CCOC(=O)c1[nH]c2ccc(OC)c3CC[C@H](CNC(C)=O)c1c23 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
